An unusual association of Morning Glory Syndrome with chronic myeloid leukemia-Philadelphia chromosome

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Chronic myeloid leukemia with an unusual paraneoplastic syndrome.

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Patient with Morning Glory syndrome

A 6-year-old patient was referred to our ophthalmology service because of an ocular deviation (esotropia) on the right eye for 3 years. Best-corrected visual acuity in right eye and 20/20 in left eye. According to the Krimsky test, the patient showed 15 prism dioptres esotropia in right eye. No changes were observed in biomicroscopy of both eyes and funduscopy of left eye was normal. An optical...

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Unusual ophthalmic manifestation in chronic myeloid leukemia: A case report

Background: Chronic myeloid leukemia (CML) is a myeloproliferative hematopoietic malignancy with a heterogeneous proliferation of hematopoietic cells in the bone marrow. The ocular manifestations are rare symptoms of CML. In this case report, a CML patient with retinal hemorrhage is reported as an uncommon symptom. Case presentation: A 35-year-old man was referred due to decreased right eye vi...

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Isodicentric Philadelphia chromosome: an uncommon chromosomal abnormality in the chronic phase of chronic myeloid leukemia (CML)

An isodicentric Philadelphia chromosome is an uncommon finding previously described as a secondary chromosomal abnormality in accelerated- or blast-phase of chronic myeloid leukemia (CML) with resistance to imatinib mesylate or dasatinib. Here, we present a case with idic(Ph) chromosome identified at initial diagnosis in a patient with chronic-phase CML.

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ژورنال

عنوان ژورنال: Journal of Family Medicine and Primary Care

سال: 2020

ISSN: 2249-4863

DOI: 10.4103/jfmpc.jfmpc_892_20